BINDING MOIETIES BASED ON SHARK IgNAR DOMAINS

The present invention relates to immunoglobulin new antigen receptors (IgNARs) from fish and uses thereof. In particular, the present invention relates to modified IgNAR variable domains and to domains from members of the immunoglobulin superfamily that have been modified to include structural featu...

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Hauptverfasser: STRELTSOV, VICTOR, IRVING, ROBERT, ALEXANDER, SIMMONS, DAVID, PETER, GRIFFITHS, KATHERINE, MERNE, HENDERSON, KYLIE, ANNE, HUDSON, PETER, BARRACLOUGH, MILES, MACKAY, VARGHESE, JOSEPH, NOOZHUMUTRY, NUTTAL, STEWART, CARMICHAEL, JENNIFER, ANN
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to immunoglobulin new antigen receptors (IgNARs) from fish and uses thereof. In particular, the present invention relates to modified IgNAR variable domains and to domains from members of the immunoglobulin superfamily that have been modified to include structural features derived from IgNAR variable domains.