3,4-DISUBSTITUTED MALEIMIDES FOR USE AS VASCULAR DAMAGING AGENTS
This invention relates to novel compounds of Formula (I) for use as vascular damaging agents: Formula (I) wherein R, R , R , R , AR , AR , AR , p, q and r are as described in the specification. The invention also relates to methods for preparing compounds of Formula (I), to their use as medicaments...
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creator | HARRIS, CRAIG STEVEN BOYLE, FRANCIS THOMAS GIBSON, KEITH ARNOULD, JEAN-CLAUDE |
description | This invention relates to novel compounds of Formula (I) for use as vascular damaging agents: Formula (I) wherein R, R , R , R , AR , AR , AR , p, q and r are as described in the specification. The invention also relates to methods for preparing compounds of Formula (I), to their use as medicaments (including methods for the treatment of angiogenesis or disease states associated with angiogenesis) and to pharmaceutical compositions containing compounds of Formula (I). |
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subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | 3,4-DISUBSTITUTED MALEIMIDES FOR USE AS VASCULAR DAMAGING AGENTS |
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