3,4-DISUBSTITUTED MALEIMIDES FOR USE AS VASCULAR DAMAGING AGENTS

This invention relates to novel compounds of Formula (I) for use as vascular damaging agents: Formula (I) wherein R, R , R , R , AR , AR , AR , p, q and r are as described in the specification. The invention also relates to methods for preparing compounds of Formula (I), to their use as medicaments...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HARRIS, CRAIG STEVEN, BOYLE, FRANCIS THOMAS, GIBSON, KEITH, ARNOULD, JEAN-CLAUDE
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:This invention relates to novel compounds of Formula (I) for use as vascular damaging agents: Formula (I) wherein R, R , R , R , AR , AR , AR , p, q and r are as described in the specification. The invention also relates to methods for preparing compounds of Formula (I), to their use as medicaments (including methods for the treatment of angiogenesis or disease states associated with angiogenesis) and to pharmaceutical compositions containing compounds of Formula (I).