Solid pharmaceutical dispersions with enhanced bioavailabilty

Spray dried solid dispersions comprising a sparingly soluble drug and hydroxypropylmethylcellulose acetate succinate (HPMCAS) provide increased aqueous solubility and/or biavailability in a use environment.

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Bibliographische Detailangaben
Hauptverfasser: Curatolo, William John, Herbig, Scott Max, Nightingale, James Alan Schriver
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:Spray dried solid dispersions comprising a sparingly soluble drug and hydroxypropylmethylcellulose acetate succinate (HPMCAS) provide increased aqueous solubility and/or biavailability in a use environment.