ACTIVATORS OF HEXOSAMINE BIOSYNTHESIS AS INHIBITORS OF INJURY INDUCED BY ISCHEMIA OR HEMORRHAGIC SHOCK

ACTIVATORS OF HEXOSAMINE BIOSYNTHESIS AS INHIBITORS OF INJURY INDUCED BY ISCHEMIA OR HEMORRHAGIC SHOCK

Disclosed herein are compositions and methods for preserving cell, tissue, or organ transplants and cultures by increasing the concentration of an intracellular metabolite of the hexosamine biosynthetic pathway. Also described herein are methods of reducing pathogenic effects in a subject by increas...

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Bibliographische Detailangaben
Hauptverfasser: CHATHAM, JOHN, CHAUDRY, IRSHAD, BOUNELIS, PAM, MARCHASE, RICHARD, PANG, YI
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Disclosed herein are compositions and methods for preserving cell, tissue, or organ transplants and cultures by increasing the concentration of an intracellular metabolite of the hexosamine biosynthetic pathway. Also described herein are methods of reducing pathogenic effects in a subject by increasing the concentration of an intracellular metabolite of the hexosamine biosynthetic pathway.