Hemostatic cross-linked dextran beads useful for rapid blood coagulation and hemostatis

Provided herein is the use of a cross-linked polysaccharide bead or grain for the manufacture of a composition for arresting bleeding and inducing rapid blood coagulation and clot formation at a bleeding or wound site of a mammal, a hemostatic wound dressing comprising cross-linked polysaccharide be...

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Bibliographische Detailangaben
Hauptverfasser:	COCHRUM, KENT, C, BENINSIG, FRANKLIN, M, GUNTHER, ROBERT, A, JEMTRUD, SUSAN, A
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BANDAGES, DRESSINGS OR ABSORBENT PADS CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS BASED THEREON DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORGANIC MACROMOLECULAR COMPOUNDS ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROSTHESES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP TREATMENT OR PROTECTION OF EYES OR EARS
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Beschreibung
Zusammenfassung:	Provided herein is the use of a cross-linked polysaccharide bead or grain for the manufacture of a composition for arresting bleeding and inducing rapid blood coagulation and clot formation at a bleeding or wound site of a mammal, a hemostatic wound dressing comprising cross-linked polysaccharide beads or grains associated with gauze, a novel hemostatic polymer composition comprising a substance containing uncharged organic hydroxyl groups and a substance containing at least one of a halogen atom and an epoxy group, which is characterized as inducing rapid blood coagulation and hemostasis at a wound or bleeding site. Methods of use of the novel polymer composition are also provided.