1,4-DIARYL-DIHYDROPYRIMIDIN-2-ONES AND THEIR USE AS HUMAN NEUTROPHIL ELASTASE INHIBITORS

The invention relates to novel 3,4-dihydropyrimidin-2(1H)-one derivatives having the formula processes for their preparation, and their use in compositions, and in the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure developm...

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Bibliographische Detailangaben
Hauptverfasser: PERNERSTORFER, JOSEF, GIELEN-HAERTWIG, HEIKE, ALBRECHT, BARBARA, LI, VOLKHART, SCHLEMMER, KARL-HEINZ, TELAN, LEILA, KELDENICH, JOERG
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention relates to novel 3,4-dihydropyrimidin-2(1H)-one derivatives having the formula processes for their preparation, and their use in compositions, and in the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.