PROCESS FOR CELL CULTURING BY CONTINUOUS PERFUSION AND ALTERNATING TANGENTIAL FLOW

PROCESS FOR CELL CULTURING BY CONTINUOUS PERFUSION AND ALTERNATING TANGENTIAL FLOW

The invention relates to a perfusion culture comprising a cell culture medium and animal cells that easily or inherently form aggregates during culturing, wherein said animal cells are present in said perfusjion culture at a viable cell density of at least 80x10 6 cells per ml and wherein not more t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CROWLEY, JOHN, WUEBBEN, MAIKE, COCO MARTIN, JOSE MANUEL
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:The invention relates to a perfusion culture comprising a cell culture medium and animal cells that easily or inherently form aggregates during culturing, wherein said animal cells are present in said perfusjion culture at a viable cell density of at least 80x10 6 cells per ml and wherein not more than 5% of the total amount of cells comprise aggregates of 5 cells or more.