ACYLAMINOTHIAZOLE DERIVATIVES AND USE THEREOF AS BETA-AMYLOID INHIBITORS

Compounds of formula (I) as defined herein: inhibit the formation of the -amyloid peptide ( -A4) and are, therefore, useful in the treatment of pathologies in which a -amyloid peptide ( -A4) formation inhibitor provides a therapeutic benefit. Particular such pathologies are senile dementia, Alzheime...

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Hauptverfasser:	BALTZER, SYLVIE, PASCAL, MARC, VAN DORSSELAER, VIVIANE
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds of formula (I) as defined herein: inhibit the formation of the -amyloid peptide ( -A4) and are, therefore, useful in the treatment of pathologies in which a -amyloid peptide ( -A4) formation inhibitor provides a therapeutic benefit. Particular such pathologies are senile dementia, Alzheimer's disease, Down's syndrome, Parkinson's disease, amyloid angiopathy, cerebrovascular disorders, frontotemporal dementias and Pick's disease, post-traumatic dementias, pathologies linked to neuroinflammatory processes, Huntington's disease and Korsakov's syndrome.