CHELATE BASED SCAFFOLDS IN TUMOR TARGETING

This invention relates to novel complexes that can be used to target tumor cells. The complexes include a ligand that can bind metal ions including radioactive lanthanide ions. The complexes can mimic alphanubeta3 integrin receptor antagonists and deliver the complexed radioactive metals to the tumo...

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Bibliographische Detailangaben
Hauptverfasser:	SUHR, ROBERT, G, GARLICH, JOSEPH, R, PATTERSON, MARY
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to novel complexes that can be used to target tumor cells. The complexes include a ligand that can bind metal ions including radioactive lanthanide ions. The complexes can mimic alphanubeta3 integrin receptor antagonists and deliver the complexed radioactive metals to the tumor cells.