PYRIDOPYRIMIDINONES FOR THE TREATMENT OF CANCER DISEASES

The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and X' have the designations cited in patent claim 1. Said compounds are inhibitors of tyrosine kinases, especially TIE-2, and Raf kinases, and can, inter alia, be used for the treatment of tumors.

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Hauptverfasser: RAUTENBERG, WILFRIED, JONCZYK, ALFRED, SOLER RIERA, MARTA, MITJANS, FRANCESC, ROSELL-VIVES, ELISABET, ACKERMANN, KARL-AUGUST, ADAN, JAUME, HOELZEMANN, GUENTER, STAEHLE, WOLFGANG, CRASSIER, HELENE
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creator RAUTENBERG, WILFRIED
JONCZYK, ALFRED
SOLER RIERA, MARTA
MITJANS, FRANCESC
ROSELL-VIVES, ELISABET
ACKERMANN, KARL-AUGUST
ADAN, JAUME
HOELZEMANN, GUENTER
STAEHLE, WOLFGANG
CRASSIER, HELENE
description The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and X' have the designations cited in patent claim 1. Said compounds are inhibitors of tyrosine kinases, especially TIE-2, and Raf kinases, and can, inter alia, be used for the treatment of tumors.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PYRIDOPYRIMIDINONES FOR THE TREATMENT OF CANCER DISEASES
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