PYRIDOPYRIMIDINONES FOR THE TREATMENT OF CANCER DISEASES

The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and X' have the designations cited in patent claim 1. Said compounds are inhibitors of tyrosine kinases, especially TIE-2, and Raf kinases, and can, inter alia, be used for the treatment of tumors.

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Bibliographische Detailangaben
Hauptverfasser:	RAUTENBERG, WILFRIED, JONCZYK, ALFRED, SOLER RIERA, MARTA, MITJANS, FRANCESC, ROSELL-VIVES, ELISABET, ACKERMANN, KARL-AUGUST, ADAN, JAUME, HOELZEMANN, GUENTER, STAEHLE, WOLFGANG, CRASSIER, HELENE
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and X' have the designations cited in patent claim 1. Said compounds are inhibitors of tyrosine kinases, especially TIE-2, and Raf kinases, and can, inter alia, be used for the treatment of tumors.