AMIDOMETHYL SUBSTITUTED 1-(CARBOXYALKYL)-CYCLOPENTYLCARBONYLAMINO-BENZAZEPINE-N-ACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS

Described are novel compounds with neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity of the general formula (I), wherein the substituents R , R , R and R have the meanings given in the description and also medicaments containing these compounds, in particular...

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Hauptverfasser:	PAHL, AXEL, MESSINGER, JOSEF, ZIEGLER, DIETER, WESKE, MICHAEL, HOEFER, CONSTANZE, KARIMI-NEJAD, YASMIN, IKONOMIDOU, HRISSANTHI, FISCHER, YVAN, TURSKI, LECHOSLAW, HOELTJE, DAGMAR, MICHAELIS, KATHRIN
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Described are novel compounds with neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity of the general formula (I), wherein the substituents R , R , R and R have the meanings given in the description and also medicaments containing these compounds, in particular medicaments suitable for treating or preventing cardiovascular diseases, sexual dysfunction and/or adverse conditions associated with apoptosis.