Antibiotic drosocin derivatives

The invention concerns derivatives of drosocin which have an increased half-life in mammalian serum by substituting one or more of the amino acid residues of wild type drosocin with another amino acid or a peptidomimetic moiety capable of replacing said amino acid. These derivatives can be used for...

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Hauptverfasser: VAN BOOM, JACOBUS HUBERTUS, NOORT, DANIEL, OVERKLEEFT, HERMAN STEVEN, VAN HOOFT, PETRUS ALBERTUS VENANTIA, DE VISSER, PETER CHRISTIAN
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creator VAN BOOM, JACOBUS HUBERTUS
NOORT, DANIEL
OVERKLEEFT, HERMAN STEVEN
VAN HOOFT, PETRUS ALBERTUS VENANTIA
DE VISSER, PETER CHRISTIAN
description The invention concerns derivatives of drosocin which have an increased half-life in mammalian serum by substituting one or more of the amino acid residues of wild type drosocin with another amino acid or a peptidomimetic moiety capable of replacing said amino acid. These derivatives can be used for antibiotic therapy or in a bacteriocidal composition.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Antibiotic drosocin derivatives
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