ANAPLASTIC LYMPHOMA KINASE MODULATORS AND METHODS OF USE

The present invention comprises compounds and pharmaceutical compositions comprising the compounds that are inhibitors of ALK. The invention also comprises methods of using the compounds and compositions to treat diseases mediated by ALK, including diseases such as cancer, immunological disorders, c...

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Hauptverfasser: MANALO, JEAN-CLAIRE L, BUSSENIUS, JOERG, KENNEDY, ABIGAIL R, PETO, CSABA J, DUBENKO, LARISA, KHOURY, RICHARD G, CURTIS, JEFFRY KIMO, BLAZEY, CHARLES M, COSTANZO, SIMONA, KIM, ANGIE I, BOWLES, OWEN JOSEPH, ANAND, NEEL KUMAR, RICE, KENNETH D, TSANG, TSZE H
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention comprises compounds and pharmaceutical compositions comprising the compounds that are inhibitors of ALK. The invention also comprises methods of using the compounds and compositions to treat diseases mediated by ALK, including diseases such as cancer, immunological disorders, cardiovascular diseases, and other degenerative disorders.