Use of fibrinolytic metalloproteinases for treating blood clots

A method is provided for the localized intravascular administration of a fibrinolytic metalloproteinase to a human subject in amounts that are both safe and effective to lyse an occluding fibrin-containing blood clot, while also avoiding the neutralizing effects of ± 2 -macroglobulin in the circulat...

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Bibliographische Detailangaben
1. Verfasser: TOOMBS, CHRISTOPHER FRANCIS
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A method is provided for the localized intravascular administration of a fibrinolytic metalloproteinase to a human subject in amounts that are both safe and effective to lyse an occluding fibrin-containing blood clot, while also avoiding the neutralizing effects of ± 2 -macroglobulin in the circulating blood.