PEPTIDE HAVING APOPTOSIS-INHIBITING ACTIVITY

PEPTIDE HAVING APOPTOSIS-INHIBITING ACTIVITY

A peptide consisting of part of the amino acid sequence of SEQ ID No: 8 and having an amino acid sequence of SEQ ID No: 1 or SEQ ID No: 2, e.g., a peptide consisting of the amino acid sequence of any one of SEQ ID Nos: 1 to 5, has an excellent apoptosis-suppressive activity. Therefore, a peptide con...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: TABE, HIROKAZU, TASHIRO, ETSU, OHMORI, YUSUKE, IMOTO, MASAYA
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A peptide consisting of part of the amino acid sequence of SEQ ID No: 8 and having an amino acid sequence of SEQ ID No: 1 or SEQ ID No: 2, e.g., a peptide consisting of the amino acid sequence of any one of SEQ ID Nos: 1 to 5, has an excellent apoptosis-suppressive activity. Therefore, a peptide consisting of part of the amino acid sequence of SEQ ID No: 8 and having an amino acid sequence of SEQ ID No: 2, particularly SEQ ID No: 1, is useful as a pharmaceutical composition for a Bax-dependent apoptosis-induced disease, such as a neurodegenerative disease.