RADIOLABELED CANNABINOID-1 RECEPTOR MODULATORS

The present invention relates to particular radiolabeled Cannabinoid-1 (CB1) receptor modulators, and methods of using these modulators for labeling and diagnostic imaging of Cannabinoid-1 receptors in mammals, particularly humans. In addition, intermediates useful for the synthesis of the radiolabe...

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Hauptverfasser: HAMILL, TERENCE, G, LIU, PING, HAGMANN, WILLIAM, K, LIN, LINUS, S, GOULET, MARK, T, CHEN, ALEX, M, JEWELL, JAMES, P, BURNS, DONALD, H, GIBSON, RAYMOND, E, PERESYPKIN, ANDREY, V
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to particular radiolabeled Cannabinoid-1 (CB1) receptor modulators, and methods of using these modulators for labeling and diagnostic imaging of Cannabinoid-1 receptors in mammals, particularly humans. In addition, intermediates useful for the synthesis of the radiolabeled Cannabinoid-1 receptor modulators are also disclosed, as well as the processes for synthesizing the radiolabeled Cannabinoid-1 receptor modulators. Still further, formulations of the radiolabeled Cannabinoid-1 receptor compounds are described.