LIGAND ANALYSIS

Methods for the analysis of receptor-ligand pairs are herein described. The methods can provide information about the binding affinity of a ligand to a receptor or can provide information about the binding kinetics of a ligand to a receptor. In some instances, the methods provide a very general syst...

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Bibliographische Detailangaben
Hauptverfasser: AKYUZ, CAN, D, NASH, HUW, M, MOALLEMI, CIAMAC, MAKARA, GERGELY, M, ANNIS, ALLEN, D, LEE, WILLIAM, H, ZHENG, ZHONGLI
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Methods for the analysis of receptor-ligand pairs are herein described. The methods can provide information about the binding affinity of a ligand to a receptor or can provide information about the binding kinetics of a ligand to a receptor. In some instances, the methods provide a very general system for evaluating and/or optimizing receptor-ligand interactions, which can be applied to a variety of types of receptor-ligand interactions, for example protein-small molecule interactions.