ECDYSONE RECEPTOR LIGAND-BINDING DOMAIN STRUCTURE

The present invention relates to structural studies of the functional insect ecdysone receptor. More particularly, the invention relates to the crystal structure of the whitefly ecdysone receptor ligand-binding domain, specifically that of Bemisia tabaci, and uses of the crystal and related structur...

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Hauptverfasser: EPA, VIDANA, C, NOYCE, LEONIE, HANNAN, GARRY, N, PILLING, PATRICIA, CARMICHAEL, JENNIFER, A, LOVRECZ, GEORGE, O, LAWRENCE, MICHAEL, C, HILL, RONALD, J, GRAHAM, LLOYD, WINKLER, DAVID
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to structural studies of the functional insect ecdysone receptor. More particularly, the invention relates to the crystal structure of the whitefly ecdysone receptor ligand-binding domain, specifically that of Bemisia tabaci, and uses of the crystal and related structural information to select and screen for compounds that interact with the receptor.