AMPHIPHILIC TRISULFONATED PORPHYRAZINES FOR PHOTODYNAMIC APPLICATIONS IN MEDICINE

Disclosed herein are novel trisulfonated tribenzo-mononahptho-porphyrazines, processes for making them and their application as improved photosensitizing drugs for the treatment of various medical conditions by photodynamic therapy (PDT). These water-soluble amphiphilic porphyrazines are substituted...

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Bibliographische Detailangaben
Hauptverfasser: VAN LIER, JOHANNES E, TIAN, HONGJIAN, ALI, HASRAT, HASSESSIAN, HAROUTIOUN MINAS, CAUCHON, NICOLE
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Disclosed herein are novel trisulfonated tribenzo-mononahptho-porphyrazines, processes for making them and their application as improved photosensitizing drugs for the treatment of various medical conditions by photodynamic therapy (PDT). These water-soluble amphiphilic porphyrazines are substituted with different alkylyl, aryl, aminoalkyl and aminoaryl groups, with or without carboxyl moeity.