METHOD FOR PREPARING THERMOFORMED COMPOSITIONS CONTAINING ACRYLIC POLYMER BINDERS, PHARMACEUTUAL DOSAGE FORMS AND METHODS OF PREPARING THE SAME

METHOD FOR PREPARING THERMOFORMED COMPOSITIONS CONTAINING ACRYLIC POLYMER BINDERS, PHARMACEUTUAL DOSAGE FORMS AND METHODS OF PREPARING THE SAME

Thermoformed or hot melt extruded pharmaceutical compositions containing an active pharmaceutical ingredient, acrylic enteric polymer and plasticizer are disclosed. Methods of making the same as well as various pharmaceutical dosage forms are also disclosed. In preferred aspects, a thermoformable mi...

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Bibliographische Detailangaben
Hauptverfasser: FEGELY, KURT, A, CROWLEY, MICHAEL, MCGINITY, JAMES, W, FARRELL, THOMAS, P, YOUNG, CHRISTOPHER R
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Thermoformed or hot melt extruded pharmaceutical compositions containing an active pharmaceutical ingredient, acrylic enteric polymer and plasticizer are disclosed. Methods of making the same as well as various pharmaceutical dosage forms are also disclosed. In preferred aspects, a thermoformable mixture is in a powder form and includes an active ingredient, plasticizer, acrylic polymer and optional excipients which enhance the performance of the extrudate after being incorporated into a dosage form.