IMIDAZOLIN-2-YLAMINOPHENYL AMIDES AS IP ANTAGONISTS

IMIDAZOLIN-2-YLAMINOPHENYL AMIDES AS IP ANTAGONISTS

Compounds effective as IP receptor modulators, particularly IP receptor antagonists, that are of the formula I: wherein A, R1, R2, R3 and R4 are as defined in the specification; and individual isomers, racemic or non-racemic mixtures of isomers, and pharmaceutically acceptable salts or solvates ther...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LOPEZ-TAPIA, FRANCISCO, JAVIER, KEITZ, PAUL, FRANCIS, O'YANG, COUNDE, JAHANGIR, ALAM
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Compounds effective as IP receptor modulators, particularly IP receptor antagonists, that are of the formula I: wherein A, R1, R2, R3 and R4 are as defined in the specification; and individual isomers, racemic or non-racemic mixtures of isomers, and pharmaceutically acceptable salts or solvates thereof. Also disclosed are pharmaceutical compositions containing such compounds and methods for their use as therapeutic agents.