BENZOPYRAN COMPOUNDS USEFUL FOR TREATING INFLAMMATORY CONDITIONS

The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 Wherein Z, X, R1, R2, R3, and R4 are as described in the...

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Hauptverfasser: BROWN, DAVID, LOUIS, TALLEY, JOHN, J, YU, YI, HAMPER, BRUCE, CAMERON, KOSZYK, FRANCIS, WANG, LIJUAN, JANE, HALLINAN, E., ANN, SPRINGER, JOHN, ROBERT, ASTON, KARL, WILLIAM, XING, LI, LIAO, SUBO, DEPROW, ANGELA, LIMBURG, DAVID, CH, MCCALL, JOHN, MICHAEL, CARTER, JEFFERY, STEVEN, LUDWIG, CINDY, FLETCHER, THERESA, HUFF, RENEE, KIEFER, JAMES, R., JR, KRAMER, STEVEN
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 Wherein Z, X, R1, R2, R3, and R4 are as described in the specification.