LABELLING AGENTS FOR MASS SPECTROMETRY COMPRISING TERTIARY AMINES

LABELLING AGENTS FOR MASS SPECTROMETRY COMPRISING TERTIARY AMINES

Provided is a method for characterizing a molecule by mass spectrometry, which molecule comprises one or more free amino groups, which method comprises: (a) reacting one or more free amino groups in the molecule with a mass tag reagent comprising a reactive functionality capable of reacting with an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KUHN, KARSTEN, REUSCHLING, DIETER, HAMON, CHRISTIAN, SCHAEFER, JUERGEN, THOMPSON, ANDREW
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Beschreibung
Zusammenfassung:Provided is a method for characterizing a molecule by mass spectrometry, which molecule comprises one or more free amino groups, which method comprises: (a) reacting one or more free amino groups in the molecule with a mass tag reagent comprising a reactive functionality capable of reacting with an amino group, and a tertiary amino group linked to the reactive functionality; and (b) characterizing the molecule by mass spectrometry.