PIPERIDINE DERIVATIVES AS CCR5 ANTAGONISTS

PIPERIDINE DERIVATIVES AS CCR5 ANTAGONISTS

The present invention relates to compounds of formula (I) or a pharmaceutically acceptable derivatives thereof, useful in the treatment of prophylazis of CCR5-related diseases and disorders, for example, in the inhibition of HIV replication, the prevention or treatment of HIV infection, and in the t...

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Hauptverfasser: DEANDA, JR. FELIX, CHONG, PEK YOKE, PECKHAM, JENNIFER POOLE, BOROS, ERIC EUGENE, DUAN, MAOSHENG, THOMPSON, JAMES BENJAMIN, KAZMIERSKI, WIESLAW MIECZYSLAW, AQUINO, CHRISTOPHER JOSEPH, KOBLE, CECILIA SUAREZ, BIFULCO, NEIL, MCLEAN, ED WILLIAMS, PERKINS, ANGILIQUE C, CHAUDER, BRIAN ANDREW, VANDERWALL, DANA
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to compounds of formula (I) or a pharmaceutically acceptable derivatives thereof, useful in the treatment of prophylazis of CCR5-related diseases and disorders, for example, in the inhibition of HIV replication, the prevention or treatment of HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).