VACCINE COMPRISING MIXTURES OF MULTIVALENT MENINGOCOCCAL OUTER MEMBRANE VESCILES

The present invention relates to vaccine compositions for the effective prevention of neisserial, preferably meningococcal, disease. The vaccine of the invention comprise a multivalent meningococcal bled composition comprising at least one bleb with homologous bactericidal activity which is derived...

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Bibliographische Detailangaben
Hauptverfasser: DESMONS, PIERRE, M, POOLMAN, JAN, DOMINGUEZ ALVAREZ, FRANCISCO, J, BARBERA MORALES, RAMON, FAUSTINO
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to vaccine compositions for the effective prevention of neisserial, preferably meningococcal, disease. The vaccine of the invention comprise a multivalent meningococcal bled composition comprising at least one bleb with homologous bactericidal activity which is derived from a meningococcal strain with a serosubtype that is prevalent in a country of use, and at least one bleb with heterologous bacterial activity which is derived from a meningococcal strain which need not have a serosubtype that is prevalent in the country of use.