PROCESS FOR PRODUCING PAROXETINE HYDROCHLORIDE HYDRATE

PROCESS FOR PRODUCING PAROXETINE HYDROCHLORIDE HYDRATE

A process for preparing a paroxetine hydrochloride hydrate, comprising reacting (3S, 4R)-1-tert-butoxycarbonyl-4-(4-fluorophenyl)-3-Ä(3,4-methylenedioxy)phenoxymethylÜpiperidine with hydrogen chloride in the presence of water, and allowing crystals to separate out from the resulting reaction mixture...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: YAMAZAKI, SHIGEYA, YOSHIKAWA, TAICHI
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A process for preparing a paroxetine hydrochloride hydrate, comprising reacting (3S, 4R)-1-tert-butoxycarbonyl-4-(4-fluorophenyl)-3-Ä(3,4-methylenedioxy)phenoxymethylÜpiperidine with hydrogen chloride in the presence of water, and allowing crystals to separate out from the resulting reaction mixture in the presence of water.