TRICYCLIC TETRAHYDROQUINOLINE ANTIBACTERIAL AGENTS

The present invention is directed to tricyclic tetrahydroquinoline compounds of formula I, and pharmaceutically acceptable salts thereof wherein the variables R1, R2, R3, R4, R5, R20 and X are as described herein and to pharmaceutical compositions thereof, that exhibit useful antibacterial activity...

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Bibliographische Detailangaben
Hauptverfasser:	MCNAMARA, D. J, TOOGOOD, P. L, BARBACHYN, M. R, ROMERO, DONNA L, DOBROWOLSKI, P. J, RUBLE, JAMES, CRAIG, SHERRY, D. A, HURD, A. R, THOMASCO, L. M, ROMERO, A. G, BUNDY, GORDON, L, MARTIN, GARY, E, PALMER, JOHN, RAYMOND
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention is directed to tricyclic tetrahydroquinoline compounds of formula I, and pharmaceutically acceptable salts thereof wherein the variables R1, R2, R3, R4, R5, R20 and X are as described herein and to pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.