CRYSTAL STRUCTURE OF ERBB2 AND USES THEREOF

More particularly, the present invention relates to the crystal structure of the ErbB2, in particular the crystal structure of an extracellular portion of ErbB2 and to methods of using the crystal and related structural information to screen for and design compounds that interact with ErbB2, or vari...

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Hauptverfasser: GARRETT, THOMAS, PETER, JOHN, LOU, MEIZHEN, JORISSEN, ROBERT, NICHOLAS, LOVRECZ, GEORGE, OSCAR, ELLEMAN, THOMAS, CHARLES, BURGESS, ANTONY, WILKES, MCKERN, NEIL, MORETON, WARD, COLIN, WESLEY, ADAMS, TIMOTHY, EDWARD
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:More particularly, the present invention relates to the crystal structure of the ErbB2, in particular the crystal structure of an extracellular portion of ErbB2 and to methods of using the crystal and related structural information to screen for and design compounds that interact with ErbB2, or variants of thereof.