ASPARTYL PROTEASE INHIBITOR AS A NEMATODE ALLERGEN

The present invention is broadly directed to novel nematode allergens (polypeptides) and associated amino acid and nucleotide sequences including functional fragments and variants thereof to identify animals that are capable of becoming naturally resistant to nematodes. In particular, the present in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	MCNEILL, MARGARET, MARY, SHAW, RICHARD, JOHN, MAASS, DAVID, RICHARD, SHOEMAKER, CHARLES, BIX
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention is broadly directed to novel nematode allergens (polypeptides) and associated amino acid and nucleotide sequences including functional fragments and variants thereof to identify animals that are capable of becoming naturally resistant to nematodes. In particular, the present invention concerns the use of these molecules to, assist in selective breeding of animals capable of becoming naturally resistant to nematode infections. More, particularly, the invention is directed towards the use of nucleic acid molecules and polypeptides, which are the same or functional variants of, aspartyl protease inhibitors: (Tco-Aspin), of Trichostrongylus colubriformis; and/or (Oc-Aspin), of Ostertagia circumcincta; and/or (Hc-Aspin) Haemonchus contortus in identifying animals that are innately more disposed to nematodes.