HYDROPHOBIC MALDI PLATE AND PROCESS FOR MAKING A MALDI PLATE HYDROPHOBIC

A sample plate for a MALDI process is provided which comprises an electrically conductive substrate having a hydrophobic coating whose thickness and hydrophobic character can be modified by changing the coating substrate and/or the concentration of the substrate. Different coating substances that ha...

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Bibliographische Detailangaben
Hauptverfasser:	HAFF, LAWRENCE, A, CAMPBELL, JENNIFER, M, TOMLINSON, ANDREW, J, SMIRNOV, IGOR, P, MURPHY, CHERYL, E
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	ADHESIVES APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BASIC ELECTRIC ELEMENTS BEER BIOCHEMISTRY CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE CHEMISTRY DYES ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS ELECTRICITY ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MISCELLANEOUS APPLICATIONS OF MATERIALS MISCELLANEOUS COMPOSITIONS MUTATION OR GENETIC ENGINEERING NATURAL RESINS PAINTS PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS POLISHES POLISHING COMPOSITIONS OTHER THAN FRENCH POLISH SKI WAXES SPIRITS TESTING TRANSPORTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	A sample plate for a MALDI process is provided which comprises an electrically conductive substrate having a hydrophobic coating whose thickness and hydrophobic character can be modified by changing the coating substrate and/or the concentration of the substrate. Different coating substances that have provided optimal performance of the sample plate for reproducible deposition and analysis by MALDI-MS and MALDI-MS/MS processes of analyte mixtures include synthetic waxes such as paraffin compositions, lipids, organic acids, silicon-containing compounds, silica polymers and natural waxes. Metal polishes that have been used to clean and regenerate plate surfaces have also provided a sample plate that has optimal performance for reproducible deposition and analysis by MALDI-MS and MALDI-MS/MS processes of analyte mixtures.