MAXS AS MODIFIERS OF THE AXIN PATHWAY AND METHODS OF USE

Human MAX genes are identified as modulators of the AXIN pathway, and thus are therapeutic targets for disorders associated with defective AXIN function. Methods for identifying modulators of AXIN, comprising screening for agents that modulate the activity of MAX are provided.

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Bibliographische Detailangaben
Hauptverfasser: AMUNDSEN, CRAIG, D, DORA, EMERY, G. III, LICKTEIG, KIM, GENDREAU, STEVEN, BRIAN
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Human MAX genes are identified as modulators of the AXIN pathway, and thus are therapeutic targets for disorders associated with defective AXIN function. Methods for identifying modulators of AXIN, comprising screening for agents that modulate the activity of MAX are provided.