NOVEL PROCESSES AND INTERMEDIATES FOR PREPARING TRIAZOLO-PYRIDINES
The present invention relates and intermediates to a novel process for preparing triazolo-pyridines of the formula I wherein R is selected from the group consisting of hydrogen, (C1-C6)alkyl or other suitable substituents; R is selected from the group consisting of hydrogen, (C1-C6)alkyl or other su...
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Format: | Patent |
Sprache: | eng ; fre ; ger |
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Zusammenfassung: | The present invention relates and intermediates to a novel process for preparing triazolo-pyridines of the formula I wherein R is selected from the group consisting of hydrogen, (C1-C6)alkyl or other suitable substituents; R is selected from the group consisting of hydrogen, (C1-C6)alkyl or other suitable substituents; s is an integer from 0-5; R is hydrogen or a suitable substituent and to intermediates for their preparation. The compounds prepared by the methods of the present invention are potent inhibitors of MAP kinases, preferably p38 kinase. They are useful in the treatment of inflammation, osteoarthritis, rheumatoid arthritis, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders. |
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