Templated compounds for generation of encoded molecules and directional methods using such compounds

Disclosed is a compound comprising a bifunctional chemical entity attached to a nucleoside derivative and a directing element capable of positioning the bifunctional chemical entity in a predominate direction. The compound is useful in the formation of encoded molecules by contacting a template nucl...

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Bibliographische Detailangaben
Hauptverfasser: SLOK, FRANK ABILGAARD, GLAD, SANNE SCHRODER
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:Disclosed is a compound comprising a bifunctional chemical entity attached to a nucleoside derivative and a directing element capable of positioning the bifunctional chemical entity in a predominate direction. The compound is useful in the formation of encoded molecules by contacting a template nucleic acid with one or a plurality of the compounds under conditions that provide for the formation of a complementary template, and reacting the bifunctional chemical entities to form an encoded molecule