Mutant phosphoribosylpyrophosphate synthetase and method for producing L-histidine

Mutant phosphoribosylpyrophosphate synthetase and method for producing L-histidine

There are provided a mutant bacterial PRPP synthetase feedback resistant to purine nucleotides and a method for producing L-histidine using bacterium of the Enterobacteriaceae family wherein the L-amino acid productivity of said bacterium is enhanced by use of PRPP synthetase feedback resistant to p...

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Hauptverfasser: SHAKULOV, RUSTEM SAIDOVICH, KLYACHKO, ELENA VITALIEVNA, KOZLOV, YURI IVANOVICH
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:There are provided a mutant bacterial PRPP synthetase feedback resistant to purine nucleotides and a method for producing L-histidine using bacterium of the Enterobacteriaceae family wherein the L-amino acid productivity of said bacterium is enhanced by use of PRPP synthetase feedback resistant to purine nucleotides coded by the mutant prsA gene.