Medicinal suspensions

The present invention relates to a pharmaceutical suspension having improved pH and viscosity and particle size stability and stable uniform distribution of active ingredient. The suspensions contain a therapeutically effective amount of suspended solid particles comprising pharmaceutical active ing...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: OSEI, ANTHONY A, BUCHLER, GAIL K, SHAPIRO, KENNETH B
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention relates to a pharmaceutical suspension having improved pH and viscosity and particle size stability and stable uniform distribution of active ingredient. The suspensions contain a therapeutically effective amount of suspended solid particles comprising pharmaceutical active ingredient, a thickening component, and an amino polycarboxylic acid compound and in certain embodiments, a nucleation inhibitor as a means to maintain a stable uniform suspension product. The invention further relates to their method of manufacture and use.