PRODUCTION PROCESS OF AMINOMETHYL GROUP-CONTAINING BENZAMIDE COMPOUND

PRODUCTION PROCESS OF AMINOMETHYL GROUP-CONTAINING BENZAMIDE COMPOUND

There is provided a process for producing an aminomethyl group-containing benzamide compound represented by the general formula (II): wherein -CONH2 and -X represent a substituent on the benzene ring and -CONH2 exists at the meta- or para-position of -CH2NH2, and X and n are as defined below, which...

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Bibliographische Detailangaben
Hauptverfasser: OHSHIRO, KIMITAKA, OHNISHI, YUTAKA, MIYATA, HIDEO
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:There is provided a process for producing an aminomethyl group-containing benzamide compound represented by the general formula (II): wherein -CONH2 and -X represent a substituent on the benzene ring and -CONH2 exists at the meta- or para-position of -CH2NH2, and X and n are as defined below, which comprises hydrating an aminomethyl group-containing benzonitrile compound represented by the general formula (I): wherein -CN and -X represent a substituent on the benzene ring and -CN exists at the meta- or para-position of -CH2NH2, X represents a chlorine atom or a fluorine atom, and n represents an integer of 0 to 4, provided that, when n is 2 or more, X may be the same or different