COMPOSITIONS AND METHODS FOR TREATING HEART FAILURE

Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.

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Bibliographische Detailangaben
Hauptverfasser:	FENG, BAINIAN, QIAN, XIANGPING, MORGANS, DAVID, J., JR, ELIAS, KATHLEEN, KRAYNACK, ERICA, ANNE, SMITH, WHITNEY, WALTER, LU, PU-PING, MALIK, FADY, TOMASI, ADAM, LEWIS
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.