REDUCED FORMATE POLY(ALKYLENE OXIDES) WITH REBOXETINE FOR REDUCING IMPURITY FORMATION

REDUCED FORMATE POLY(ALKYLENE OXIDES) WITH REBOXETINE FOR REDUCING IMPURITY FORMATION

Oral delivery vehicles and compositions for providing sustained release of secondary amines including reboxetine with reduced formate poly(alkylene oxide) polymers are provided. Processes for reducing the amount of the formic compounds from the polymers comprising contacting the polymers with an aci...

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Bibliographische Detailangaben
Hauptverfasser: AYER, ATUL, D, SEROFF, SYLVIA, L, LAM, ANDREW, C, YAM, NOYMI, V
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Oral delivery vehicles and compositions for providing sustained release of secondary amines including reboxetine with reduced formate poly(alkylene oxide) polymers are provided. Processes for reducing the amount of the formic compounds from the polymers comprising contacting the polymers with an acid having a Pka lower than that of formic acid are also disclosed.