COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE

The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells wherein W, Cyc, p, , X, Z, R, K-, R, R , R , R ,R ,< >I and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising comp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	VEDERAS, JOHN, CHRISTOPHER, LOPASCHUK, GARY, DAVID, DYCK, JASON, ROLAND
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells wherein W, Cyc, p, , X, Z, R, K-, R, R , R , R ,R ,< >I and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose Oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.