METHODS FOR THE IDENTIFICATION OF COMPOUNDS USEFUL FOR THE SUPPRESSION OF CHRONIC NEUROPATHIC PAIN AND COMPOSITIONS THEREOF

The invention relates to a method of screening for a compound able to modulate the activity of an N-type voltage-dependent calcium channel consisting of the Cav2.2 (alpha1B), alpha2delta1, beta1 and gamma4 subunits; wherein said compound may be in one embodiment e.g. an antibody or an antisense nucl...

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Bibliographische Detailangaben
Hauptverfasser:	BARCLAY, JANE, GANJU, PAMPOSH
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to a method of screening for a compound able to modulate the activity of an N-type voltage-dependent calcium channel consisting of the Cav2.2 (alpha1B), alpha2delta1, beta1 and gamma4 subunits; wherein said compound may be in one embodiment e.g. an antibody or an antisense nucleotide sequence.