A test device and method for detecting the presence of a residue analyte in a sample

A test device for detecting the presence of a residue analyte in a sample includes a support strip and a sample-absorbing matrix attached to the support strip. The sample-absorbing matrix has a material for absorbing an amount of the sample. The test device also includes a mobile-phase support for h...

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Bibliographische Detailangaben
Hauptverfasser:	FRANCISCO, CHERYL B, AGI-GLICKMAN, YAEL, MARKOVSKY, ROBERT J, CHARM, STANLEY E, SAUL, STEVEN J, SKIFFINGTON, RICHARD T, ZOMER, ELIEZER, DONAHUE, PAUL R, TRIVEDI, SHIFALI B, SCHEEMAKER, JOAN L
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
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Beschreibung
Zusammenfassung:	A test device for detecting the presence of a residue analyte in a sample includes a support strip and a sample-absorbing matrix attached to the support strip. The sample-absorbing matrix has a material for absorbing an amount of the sample. The test device also includes a mobile-phase support for holding a mobile-phase composition. The mobile-phase support is attached to the support strip and in contact with the sample-absorbing matrix. A mobile-phase composition is disposed on the mobile-phase support and has a receptor for binding with the analyte. The mobile-phase composition can be carried in the sample. A stationary-phase membrane is attached to the support strip and has a first membrane end in contact with the mobile-phase composition and a second membrane end. The membrane allows lateral capillary flow of the sample from the first membrane end to the second membrane end. A test zone is on the stationary-phase membrane between the first membrane end and second membrane end and having a first binder for binding with an unbound receptor. A control zone is the stationary-phase membrane between the test zone and second membrane end and has a second binder for binding with an analyte-bound receptor or residual unbound receptor.