AMLOPIDINE BEZYLATE TABLETS WITH IMPROVED STABILITY

The invention relates to amlodipine bezylate tablets with improved stability of the active ingredient and reduced in weight containing microcrystalline cellulose, a lubricant and a disintegrating agent. Said tablets comprise 4-6 % by weight of amlodipine bezylate as active ingredient together with 8...

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Bibliographische Detailangaben
Hauptverfasser: TOEMPE, PETER, THUROCZI, PALNE, SZENTGROTI, PALNE, FEKETE, PAL, GORA, LASZLONE, KIRALYNE IGNACZ, MARIA, LEVENTISZNE HUSZAR, MAGDOLNA, LONKAINE MAGYAR, OLGA
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention relates to amlodipine bezylate tablets with improved stability of the active ingredient and reduced in weight containing microcrystalline cellulose, a lubricant and a disintegrating agent. Said tablets comprise 4-6 % by weight of amlodipine bezylate as active ingredient together with 87 to 94 % by weight of microcrystalline cellulose, 1-5 % by weight of a disintegrating agent, 0.5 to 1.5 % by weight of a lubricant and 0.2 to 1.0 % by weight of colloidal silicon dioxide. The invention also relates to a process for the preparation of the said tablets.