MUTATIONS IN THE B-RAF GENE

The invention relates to mutations in B-Raf gene products. The mutations described are identified in human tumors of natural origin. These mutations are associated with cancerous phenotypes and can be used as a basis for the diagnosis of cancer, cancerous cells or a predisposition to cancer in human...

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Bibliographische Detailangaben
Hauptverfasser: WOOSTER, RICHARD, STRATTON, MIKE, FUTREAL, ANDY, MARAIS, RICHARD M, MARSHALL, CHRIS
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention relates to mutations in B-Raf gene products. The mutations described are identified in human tumors of natural origin. These mutations are associated with cancerous phenotypes and can be used as a basis for the diagnosis of cancer, cancerous cells or a predisposition to cancer in human subjects, and the development of anti-cancer therapeutics.