Image pick-up device capable of being autoclaved

The present invention provides an image pick-up device and an endoscope in which a lens member and a CCD are prevented from exposure to water vapor during autoclave sterilization, and in which the diameter of an insertion portion is narrow, a rigid tip end portion is short, and assembly is performed easily. The image pick-up device of the present invention comprises an image pick-up means (10) for capturing an optical image obtained from incident light entering a conduit of a tubular member, and outputting an image signal of the optical image, wiring means (24) extending from the image pick-up means in an opposite direction to the direction in which the incident light enters, this wiring means being capable of transmitting the image signal, and a substrate (20) which is disposed in the conduit of the tubular member, has engaging portions (21b) for engaging with the wiring means, one surface of which is substantially orthogonal to the axial direction of the tubular member, and which is formed of a member having a light-transmitting property.