N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES

Disclosed are compounds of the formula wherein the variables RN, RC, R1, R25, R2, and R3 are as defined herein. These compounds have activity as inhibitors of beta-secretase and are therefore useful in treating a variety of disorders such as Alzheimer's Disease.

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Bibliographische Detailangaben
Hauptverfasser: FANG, LARRY, MAILLARD, MICHEL, JOHN, VARGHESE, GAILUNAS, ANDREA, TENBRINK, RUTH, HOM, ROY, SEALY, JENNIFER, JAGODZINSKA, BARBARA, FRESKOS, JOHN, MICKELSON, JOHN, BECK, JAMES, P, SAMALA, LAKSHMAN
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Disclosed are compounds of the formula wherein the variables RN, RC, R1, R25, R2, and R3 are as defined herein. These compounds have activity as inhibitors of beta-secretase and are therefore useful in treating a variety of disorders such as Alzheimer's Disease.