Fluidically enhanced in vitro diagnostic test chamber

An enclosed chamber for use in a system for screening of a liquid specimen through binding assays, the enclosed chamber including an inlet, an outlet, and a plurality of discrete reactant containing regions communicated by a common reagent flow path from the inlet to the outlet, the apparatus compri...

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Hauptverfasser: ZYCHILINSKY, EMI, MARINO, DONALD, WILMARTH, BRETT, RYAN, RENEE, ZATZKE, MICHAEL, DING, KAREN, WOOLEY, C. BENJAMIN, KASSINOS, ADONIS, YAMADA, SANDY, SELL, WILLIAM J, INNERST, DIANNA
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:An enclosed chamber for use in a system for screening of a liquid specimen through binding assays, the enclosed chamber including an inlet, an outlet, and a plurality of discrete reactant containing regions communicated by a common reagent flow path from the inlet to the outlet, the apparatus comprising: a member defining on an inside thereof a plurality of wells each having a bottom for receiving a reactant; a bottom for enclosing the plurality of wells and defining between the inlet and the outlet a flow path connecting the plurality of wells into the common reagent flow path between the inlet and the outlet; and the bottom defming for each of the plurality of wells a flow diverting member defining a continuous surface, the continuous surface protruding to and toward one of the plurality of wells for deflecting fluid flowing from the inlet to the outlet into an interior of the plurality of wells for permitting washing of fluids from plurality of wells.