CONTROLLED RELEASE COMPOSITIONS FOR MACROLIDE ANTIMICROBIAL AGENTS

The present invention provides a controlled release pharmaceutical composition of an acid labile, poorly soluble drug having pH dependent solubility profile in aqueous environment. In a preferred embodiment the drug is combined with a practically water insoluble polymer an optimizing agent and optio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KHAPRA, PANKAJ, GOSAVI, ARUN S, HUSSAIN, JAVED
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention provides a controlled release pharmaceutical composition of an acid labile, poorly soluble drug having pH dependent solubility profile in aqueous environment. In a preferred embodiment the drug is combined with a practically water insoluble polymer an optimizing agent and optional additives to produce a controlled release of therapeutic agent when compositions is exposed to aqueous environment.