IMPROVED BONE GRAFT

The invention provides an osteoinductive composition for implantation at a bone defect site which comprises osteoinductive demineralized bone matrix in a carrier of hydrated polysaccharide, the type and quantity of polysaccharide present in the carrier being sufficient, upon hydration, of importing...

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Bibliographische Detailangaben
Hauptverfasser: WINTERBOTTOM, John, FORSYTH, Nanette, KNAACK, David, DIEGMAN, Michele, TRAIANEDES, Kathy
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention provides an osteoinductive composition for implantation at a bone defect site which comprises osteoinductive demineralized bone matrix in a carrier of hydrated polysaccharide, the type and quantity of polysaccharide present in the carrier being sufficient, upon hydration, of importing flowability to the composition and providing an osteoinductive activity of at least 1 as measured by the athymic rat model assay. The polysaccharide may be selected from the group consisting of starch and cellulose.